openFrame Microscope Platform
The flexible openFrame microscope stand, originating from Imperial College London & co-developed with Cairn, underpins a modular, open-source imaging platform designed to facilitate scientific innovation. Engineered for flexibility and sustainability, it allows researchers to customize optical configurations for almost any microscopy modality – from brightfield and quantitative phase imaging, to wide-field, TIRF, confocal, and super-resolved fluorescence imaging. Its open architecture encourages adaptation for cutting-edge research, e.g., incorporating electrophysiology set-ups, while its modular nature makes it ideal for training and teaching environments. By combining Cairn and Custom Scopes’s engineering skills to build on Imperial academics’ openly shared insights and innovations, openFrame-based microscopes deliver high-performance while enabling you to innovate without barriers arising from proprietary hardware and software constraints.
Widening access to advanced imaging tools is at the heart of customscopes.co.uk, Built to evolve without obsolescence, openFrame is microscopy reimagined.
- Affordable
- Sustainable
- Flexible
- Robust & stable
- open source
- Compact
Ultimate flexibility
- Reproduce complex optical configurations from academic press (e.g. 4F systems)
- Close access to objective for efficient light capture and maximum field-of-view
- Pixel alignment – precise, in-situ, control of beamsplitters
- Small platform – suitable for incubator, containment lab or field work
- Tube lens flexibility – optimised tube lens selection, can be different between ports
- Simultaneous multichannel – no need for additional components
- Macro from above – low power objective or zoom lens for macro imaging
- Focus lock option and easy access to conjugate back focal plane for alignment
- Fast z scanning – low moving mass of either the sample or objective
- Bespoke automation – motorise only the components that you need
- Rebuild and repurpose as needs change, make use of existing equiment


